Risk factors for cryptorchidism

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Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys

Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential endocrine disruptors in parental diet and occupation. In a case-control study nested within a cohort of 8,698 male births, we compared 78 crypt...

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Risk Factors for Congenital Cryptorchidism in a Prospective Birth Cohort Study

BACKGROUND Risk factors for congenital cryptorchidism were investigated in a prospective birth cohort study in Denmark and Finland from 1997 to 2001. METHODOLOGY AND PRINCIPAL FINDINGS In total, 2,496 boys were examined for cryptorchidism at birth (cryptorchid/healthy: 128/2,368) and three months old (33/2,215). Information on risk factors was obtained antenatally (questionnaire/interview) or...

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Polymorphism of exon 13 lgr8 gene as risk factors for cryptorchidism in children

Cryptorchidism refers to incomplete descend of the testes into the scrotum with the testes located in the normal tracts. The incident is 3-5% among infants born at term. The complications are infertility and testicular cancer. Cryptorchidism has a multifactorial aetiology and the role of exon 13 lgr8 gene polymorphism remains unclear. This study aims to find the frequency polymorphism of exon 1...

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Risk factors for liver cancer worldwide.

: In this short commentary, we discuss the most important risk factors for liver cancer. One of the most striking risks is infection with hepatitis B and C viruses, leading to chronic hepatitis, which may later develop into hepatocellular carcinoma (HCC). The use of alcohol may lead to cirrhosis, which is scarring the liver, is associated with 30 a more increase in HCC and 10-20 times more incr...

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Human Exposure to Endocrine-Disrupting Chemicals and Prenatal Risk Factors for Cryptorchidism and Hypospadias: A Nested Case–Control Study

BACKGROUND Exposure to xenoestrogens during pregnancy may disturb the development and function of male sexual organs. OBJECTIVE In this study we aimed to determine whether the combined effect of environmental estrogens measured as total effective xenoestrogen burden (TEXB) is a risk factor for male urogenital malformations. METHODS In a case-control study, nested in a mother-child cohort (n...

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ژورنال

عنوان ژورنال: Nature Reviews Urology

سال: 2017

ISSN: 1759-4812,1759-4820

DOI: 10.1038/nrurol.2017.90